Nanotechnology NextGen: From Treatment to Transformation in Polycystic Ovary Syndrome (PCOS)

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Authors

Mr. Rahul Pal (Young Scientist) (ed)
Faculty of Medical, Paramedical and Allied Health Sciences, Department of Pharmacy, Jagannath University, 303901, Jaipur, Rajasthan, India
https://orcid.org/0000-0003-2062-2678
Ms. Anjali Rai (ed)
Faculty of Medical, Paramedical and Allied Health Sciences, Department of Pharmacy, Jagannath University, 303901, Jaipur, Rajasthan, India
https://orcid.org/0009-0009-9037-325X
Ms. Shivani Pannu (ed)
Department of Pharmaceutics, Desh Bhagat University, Amloh Road, Mandi Gobindgarh, 147301, Punjab, India.
https://orcid.org/0000-0002-0929-7862
Km. Reena (ed)
Department of Pharmacy, Invertis Institute of Pharmacy, Invertis University, Bareilly, UP, India.
https://orcid.org/0000-0002-3545-9140
Dr. Avishikta Ray Das (ed)
Department of Pharmacy, Usha Martin University, Ranchi, Jharkhand, 835103, India.
https://orcid.org/0009-0009-4339-0081

Keywords:

Nanotechnology, Therapeutics, Polycystic Ovary Syndrome, PCOS, Nanocarriers, Personalized Nanomedicine, Antioxidants

Synopsis

Polycystic Ovary Syndrome (PCOS) is one of the most prevalent and complex endocrine–metabolic disorders affecting women of reproductive age, characterized by hyperandrogenism, chronic anovulation, insulin resistance, inflammation, and long-term cardiometabolic complications. Despite the availability of pharmacological and lifestyle-based interventions, conventional therapies often suffer from limited efficacy, systemic side effects, poor patient compliance, and an inability to address the multifactorial pathophysiology of PCOS. In this context, nanotechnology has emerged as a next-generation transformative platform capable of redefining PCOS management beyond symptomatic treatment.

This book explores the evolving role of nanotechnology-driven strategies in PCOS, spanning targeted drug delivery, enhanced bioavailability of therapeutics, controlled and sustained release systems, and precision-based intervention. Advanced nanocarriers such as polymeric nanoparticles, lipid-based systems, nanoemulsions, solid lipid nanoparticles, nanostructured lipid carriers, dendrimers, and phytochemical-loaded nanoplatforms are critically discussed for their potential to improve insulin sensitization, hormonal modulation, anti-inflammatory activity, and ovarian tissue targeting. The integration of nanotechnology with nutraceuticals, phytomedicines, gene-based therapies, and diagnostic nanodevices highlights a paradigm shift from conventional management to personalized and predictive care.

Furthermore, the book addresses translational challenges, regulatory considerations, safety and toxicity concerns, and emerging clinical evidence supporting nanomedicine-based interventions in PCOS. By bridging molecular insights with technological innovation, this volume provides a comprehensive roadmap illustrating how nanotechnology can move PCOS management from treatment toward long-term transformation. It serves as a valuable resource for researchers, clinicians, pharmaceutical scientists, and healthcare professionals seeking next-generation solutions for holistic and precision-driven PCOS care.

Chapters

References

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Advancements in lead therapeutic phytochemicals polycystic ovary syndrome: A review—PMC. (n.d.). Retrieved October 9, 2025, from https://pmc.ncbi.nlm.nih.gov/articles/PMC9868606/

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Alwan, S. H., & Al-Saeed, M. H. (2023). Silver Nanoparticles Biofabricated from Cinnamomum zeylanicum Reduce IL-6, IL-18, and TNF-ɑ in Female Rats with Polycystic Ovarian Syndrome. International Journal of Fertility and Sterility, 17(1), 80–84. https://doi.org/10.22074/IJFS.2022.539396.1189

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Front Pages

Published

15 July 2025
Copyright (c) 2025 Mr. Rahul Pal (Young Scientist), Ms. Anjali Rai, Ms. Shivani Pannu, Km. Reena, Dr. Avishikta Ray Das; Jhilli Basu, Jyoti Devi, Diksha Chauhan, Priya Jaswal, Binita Ghosh, Shantanu Prajapati, Sushant Mouraya, Sneha Patil, Nikhil Rajnani, Monal Jain, Nalini Kurup , Ranjan Kumar Singh, Komal Sharma, Mantun Prasad Gupta, Ravikant, Mahesh Singh Rajpurohit, Vaibhav Saxena, Ajay Garg, Raman Kumari, Priyanka Rani, Kamal Kumar Daal, Sami Ahmad, Sneha Chauhan, Sheelendra Kumar, Hemant Sharma, Rishabh Gupta, Shweta Singh, Tanuja, Harsh Goswami, Abhishek Tyagi, Sonal Sharma, Subhanshi Vishwas, Sami Ahmad, Kamal Kumar Daal, Divyansh Bhatnagar, Rishabh Gupta, Shweta Singh, Vandna Tiwari, Subhanshi Vishwas, Shivang Shukla, Sushant M. Ahire, Prerana S. Pawar, Shivraj P. Jadhav, Vijay V. Shewale, Chandrashekhar D. Patil, Sunil K. Mahajan, Subhanshi Vishwas

Details about the available publication format: E-Book

E-Book

ISBN-13 (15)

978-93-7185-087-2

Details about the available publication format: Book (Paperback)

Book (Paperback)

ISBN-13 (15)

978-93-7185-910-3

How to Cite

Pal, R., Rai, A., Pannu, S. ., Reena, & Das, A. R. . (Eds.). (2025). Nanotechnology NextGen: From Treatment to Transformation in Polycystic Ovary Syndrome (PCOS). Deep Science Publishing. https://doi.org/10.70593/978-93-7185-087-2
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