Tryptanthrin incorporated N/S/O heterocycles – synthesis and biological properties

DOI: https://doi.org/10.70593/978-93-7185-164-0_1

Authors

Ani Deepthi
Department of Chemistry, University of Kerala, Kerala, India
Sruthi S. L.
Department of Chemistry, University of Kerala, Kerala, India
Devika Krishnan
Department of Chemistry, University of Kerala, Kerala, India

Synopsis

The chapter describes the synthesis and biological properties of spiroheterocycles derived from tryptanthrin, a natural quinazoline alkaloid possessing numerous biological properties. Spiroheterocycles were prepared through multicomponent reactions following green protocols and were evaluated for antibacterial and anticancer properties. The noticeable potential of these molecules warrants further attention to natural quinazoline alkaloid derivatives as sources for lead compounds.

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Chapter 1

Volume

Synthetic Methods and Applications of Heterocyclic Compounds in Medicinal and Organic Chemistry

Pages

1-10

Published

14 November 2025
Copyright (c) 2025 T R Swaroop; Anupama Anjali , Swadhin Swaraj Acharya, Bibhuti Bhusan Parida, Ram Singh Jat, M. Bhanuchandra, Anjali Sharma, Rajib Panchadhayee, Aminul Islam, Pranab Ghosh, Nithesh Kumar Krishnan, Harini Bhagyaraj, Esakkimuthu Shanmugasundaram, Vikash Kumar Sonu, Apoorv Saraswat, Ani Deepthi, Sruthi S. L.; Devika Krishnan; Rajaghatta N Suresh, Kempegowda Mantelingu, Toreshettahally R Swaroop, Kanchugarakoppal S Rangappa, M Sarasija, Vijaya Lakshmi , Ramchandra Thorat, Owais Mujawar, Ram Chandra Maji, Stalin Thambusamy

How to Cite

Ani Deepthi, Sruthi S. L., & Krishnan, D. . (2025). Tryptanthrin incorporated N/S/O heterocycles – synthesis and biological properties. In T. R. Swaroop (Ed.), Synthetic Methods and Applications of Heterocyclic Compounds in Medicinal and Organic Chemistry (pp. 1-10). Deep Science Publishing. https://doi.org/10.70593/978-93-7185-164-0_1
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