Integrating Chemistry, Clinical Practice, and Pharmacoepidemiology From Molecule to Population

The book is the result of a belief that the greatest contributions in the field of therapeutic science are made on the borders of areas that were traditionally separate. The book From Molecule to Population is devoted to the light shedding on the most important chain between the design of a drug molecule and its final effect on human populations.

This journey of integration we map in four. Our starting point is the molecular basis with the studies of innovative chemical synthesis and bioactive scaffolds. This then becomes personalized therapy in clinical practice, across the translational bridge, under clinical pharmacy and close pharmacovigilance of the safety of individual patients. Lastly, we use the population-level lens and apply the systems of pharmacoepidemiology and the real-world evidence of a drug to gain insights into the extensive use, benefits, and risks of a drug.

This book targets students, scholars, clinicians in the field of pharmaceutical sciences, medicinal chemistry, clinical pharmacy, and in the area of public health. It belongs to those who want to have a unified idea of how the properties of the molecules predetermine the clinical practice and how the personal results of the patients influence the overall knowledge of the population health.

Our long run objective is to make people more collaborative and holistic minded. With links between chemical structure and population-wide effect, we will be able to help in a future where quality patient care is replicated by a smooth flow between drug development, clinical application, and safety monitoring anywhere.